repurposing

Adding a drug currently used against idiopathic pulmonary fibrosis to chemotherapy in the neoadjuvant setting increased event-free survival in patients with early HER2-negative breast cancer. The study, published in Clinical Cancer Research, 16 September, found that high levels of fibrosis…

Throughout human history, the search for a universal cure has captivated the minds of philosophers, healers and scientists across time and cultures. In Greek mythology, the goddess Panacea was believed to possess a potion to treat all afflictions. We still…

Treating acute myeloid leukaemia with losartan, a commonly used blood pressure agent, achieved the dual benefits of enhancing chemotherapy efficacy and preventing cardiotoxicity in a mouse model. The study, published in Science Translational Medicine, 19 June, demonstrated both benefits were…

Could the frantic search for drugs to treat patients severely affected by the covid-19 virus be a shot in the arm for new cancer treatments? There have been many headlines about repurposed agents, such as the highly debated antimalarial drug…

Originally developed and approved for use in diabetes, inflammation and other non-oncological diseases (even osteoarthritis in dogs), many drugs could have a pivotal role in treating cancer. And they could be more abundant than expected, according to a paper recently…